Brodifacoum TC ≥ 98% | Bromadiolone TC ≥ 98%

Brodifacoum, Brodifacoum manufacturer in China

BRODIFACOUM TC

Brodifacoum Technical Material 98% Min.
MOA’s Reg. No.: PD20070323 (✔)
China’s Hypertoxic Chemicals Permit (✔)
2017 Restricted Pesticide License (✔)
UN3027, Class 6.1, PG: I. (Steel) (✔)
Legislated Tariff No.: 293220-9011 (✔)
The most potent ‘super-warfarin’ rodenticide, ideal for controlling larger pests, features a complex 8-step synthesis process.

BROMADIOLONE TC

Bromadiolone Technical Material 98% Min.
MOA’s Reg. No.: PD20070322 (✔)
China’s Hypertoxic Chemicals Permit (✔)
2017 Restricted Pesticide License (✔)
UN3027, Class 6.1, PG: I. (Steel) (✔)
Legislated Tariff No.: 293220-9013 (✔)
The most widely used 2nd-generation anticoagulant rodenticide, a 4-step manufactured coumarin derivative.

DIFENACOUM STAGE 6

C₂₂H₂₀O, CAS#56181-66-9, Registration (✔)
Since the 2005 Industrial Policy Directory (now the 2024 edition), China has banned the production of new rodenticide active ingredients, including Difenacoum. We used to have an approved production line for producing some intermediates for export.
Synthesized in the same manner as Brodifacoum without the Bromine in initiation, ecologically safer for birds.

China’s “Hypertoxic Chemicals” License

base on the China’s “Work Safety Law” and “Catalogue of Hazardous Chemicals” since 2002

(Catalogue of Hazardous Chemicals updated to 2015 edition)

(In 2021, China’s “Work Safety Law” underwent its third revision)

(2002 – Present)

2015 Catalogue #2413 – Brodifacoum (Hypertoxic)

2015 Catalogue #2414 – Bromadiolone (Hypertoxic)

The regulatory authorities are the Ministry of Public Security (MPS) and the Ministry of Emergency Management (MEM, formerly SAWS).

“Technical Brodifacoum” and “Technical Bromadiolone” have both been classified by the WHO in Class Ia – “Extremely Hazardous,” based on acute oral LD₅₀ of 0.3 mg/kg and 1.1 mg/kg for rats, respectively. In EU, they are classified as Class I (Very Toxic) under EU Directive 67/548/EEC (now the CLP Regulation, Regulation (EC) No 1272/2008).
The “China Directory of HyperToxic Chemicals (2015 edition)” was compiled based on the list of substances labeled as “Hypertoxic” (Chinese characters: 剧毒, Mandarin: Jù Dú, meaning Extremely Toxic) in the “China Catalogue of Hazardous Chemicals (2015 Edition)” (Current) formulated by the State Administration of Work Safety (SAWS) and other relevant ministries and commissions. Compared to the “China Directory of Hypertoxic Chemicals (2002 edition),” the criteria for determining “Hypertoxic” have changed. For example, in the 2002 edition of the Directory, the acute LD₅₀ (rat oral) reference was ≤50 mg/kg, while in the 2015 edition, it has been revised to ≤5 mg/kg.
– the above from https://zh.wikipedia.org/zh-sg/剧毒化学品名录
Brodifacoum (2015 Hazard Code #2413, labeled as “Hypertoxic”) and Bromadiolone (Hazard Code #2414, labeled as “Hypertoxic”) are the highest level hazardous chemicals controlled in China. The regulatory provisions for the Hypertoxic chemicals “Brodifacoum and Bromadiolone” in China are as follows:
– General Regulations: the “Regulations on Safe Management of Hazardous Chemicals in China (2002 Edition)” (now the 2011 edition, State Council Order No. 591); and the “Catalogue of Hazardous Chemicals (2002 edtion)” (now updated 2015 edition);
– Production: the “Work Safety Law” (typically referring to the “Law of the People’s Republic of China on Work Safety (2002 Edition)” (now the 2021 Edition);
– Purchasing and Road Transportation: the “Measures for the Administration of Permits for the Purchase and Transportation of Hypertoxic Chemicals” (Ministry of Public Security Order No. 77, 2005);
– Storage: the “Public Safety Protection Requirements for Storage Facilities of Hypertoxic Chemicals and Radioactive Sources” (the standard “GA 1002-2012” promulgated by the Ministry of Public Security in 2012).
The two main authorities responsible for regulating industrial (technical material, pure) Brodifacoum and Bromadiolone are the Ministry of Public Security (MPS) and the the Ministry of Emergency Management (MEM) (formerly SAWS, the State Administration of Work Safety).
# Latest update: The SAWS General Office has issued the “Implementation Guidelines for the ‘List of Hazardous Chemicals’ (Trial) (2015)” and published the “Hazard Classification” section of the “List of Hazardous Chemicals” as an appendix. For example, Hazard Code 2413, “Brodifacoum”, has the following hazard classifications: “Acute Tox. 1; Acute Tox. 1; Acute Tox. 1; STOT RE 1; Aquatic Acute 1; Aquatic Chronic 1; Repr. 1A.”

“Hypertoxic Chemicals License” issued by MEM (formerly by SAWS)
Since 2002, in accordance with the “China’s Work Safety Law” and the “Catalogue of Hazardous Chemicals,” the production and sale of technical Bromadiolone and Brodifacoum in China have been subject to mandatory hazardous chemical licensing management, reviewed and approved by SAWS. In 2018, this responsibility was assumed by the newly established MEM. In 2021, the relocation of our factory’s new site passed the inspection by the MEM department and obtained an updated hazardous chemical license.
– Official website for verifying Hazardous Chemical Permits:
– https://whjy.mem.gov.cn/#/licenseSearch
– Please click to view the verification results for Siyang Rodenticide Factory.
# Latest update: Siyang Rodenticide Factory completed the renewal of its new MEM’s Hypertoxic Chemical Permit (Technical Brodifacoum and Technical Bromadiolone) on 24, June, 2024, which is valid until 23, June, 2027.
– Please click to view the MES’s extreme toxic chemical license.

“Directory of National Industrial Policies”

under the 2005 “China’s National Industrial Directive” of State Council

(2005 Directory updated to 2024 edition)

(2005 – Present)

China has banned NEW rodenticide manufacturers and NEW active ingredients since 2005

On December 2, 2005, China’s “National Industrial Directive” officially came into effect. That is, the “Decision of the State Council on Promulgating the ‘Interim Provisions on Promoting Industrial Structure Adjustment’ for Implementation” (GuoFa [2005] No. 40 of the State Council), which remains in effect today.
– Official link:
https://www.gov.cn/zwgk/2005-12/21/content_133214.htm
In 2005, the National Development and Reform Commission (NDRC) issued the first edition of “Directory for Guiding Industry Restructuring.” This document is a detailed regulatory document based on the 2005 “National Industrial Directive” and is commonly referred to as “National Industrial Policies” in China. Since then, the content of the directory has been adjusted several times in accordance with actual circumstances, with the latest version being the 2024 edition. The directory is divided into three categories: “encouraged,” “restricted,” and “eliminated.” The “Restricted Category” primarily refers to prohibitions on new production capacity, aiming to prevent blind expansion and redundant construction within industries.
Since the directory was first published in 2005, “highly toxic pesticides” have always been listed as “Restricted Category” up to the current 2024 edition. The directory lists all rodenticides in detail, including “Warfarin, Coumatetralyl, Bromadiolone, and Brodifacoum,” and new production projects involving these substances are prohibited.
# Latest update: China’s restrictions on the rodenticide manufacturing industry (between 2005 and 2025, a span of 20 years):
– 2005 edition, (Category II: Restricted, Paragraph 4, Section 37)
https://www.ndrc.gov.cn/xxgk/zcfb/fzggwl/200512/t20051222_960679.html
– 2011 edition (Category II: Restricted, Page 66 and 67)
https://www.gov.cn/gzdt/att/att/site1/20110426/001e3741a2cc0f20bacd01.pdf
– 2021 edition (Category II: Restricted, Paragraph 4, Section 8)
https://www.gov.cn/zhengce/2021-12/27/content_5713262.htm
– 2024 edition (Category II: Restricted, Page 88)
https://www.ndrc.gov.cn/xxgk/zcfb/fzggwl/202312/P020231229700886191069.pdf

Bromadiolone Technical Material Registration

Bromadiolone TC 98% Reg.: PD20070322. China's HyperToxic Chemical #2414. "UN3027, Class 6.1, PG: I. (Steel)." Legislated Tariff No.: "2932209013."

Brodifacoum Technical Material Registration

Brodifacoum TC 98% Reg.: PD20070323. China's HyperToxic Chemical #2413. "UN3027, Class 6.1, PG: I. (Steel)." Legislated Tariff No.: "2932209011."

C22H20O, CAS# 56181-66-9, EC# 260-034-9, "Difenacoum intermediate," the last stage before coumarin synthesis, registered under China's REACH.

China’s National Pesticide “Rodenticide Production License”

base on the “Pesticide Law” and “National Industrial Policies”

(China’s Pesticide Law updated to 2017 edition)

(Directory of National Industrial Policy update to 2024 edition)

(1997 – 2017)

Brodifacoum and Brodifacoum officially became national pesticides in 2007, and as such rodenticides production in China is subject to the issuance of a Manufacturing License by the AQSIQ, which has been taken over by the MOA (now renamed MARA) since the new pesticide law in 2017.

Siyang Rodenticide Factory is a “nationally designated rodenticide” production unit. The term “nationally designated rodenticide” refers to rodenticides that are legally produced, i.e., a technical pesticide rodenticide production enterprise. The production of technical rodenticides in China requires approval from all relevant national ministries and commissions, and a pesticide production license must be obtained before production can commence.
✔ (1) Since the implementation of the “Pesticide Management Regulations” in China in 1997, rodenticide products, as one category of pesticides, must be registered with the Ministry of Agriculture (MOA).
✔ (2) The production facilities for technical pesticide rodenticides must undergo approval by two ministries. First, the production environment assessment must be approved by the Ministry of Environmental Protection (MEP, now MEE, the Ministry of Ecology and Environment). Second, in accordance with the 2002 Regulations on the Management of Hazardous Chemicals, production safety has been implemented under the SAWS (now MEM) statutory licensing.
✔ (3) Since the establishment of the Ministry of Industry and Information Technology (MIIT) in 2008, it has taken over some of the functions previously handled by the National Development and Reform Commission (NDRC). Based on the “2005 National Industrial Directive” issued by the State Council and the “Industrial Policy Catalog” of the NDRC, the MIIT conducts inspections to verify the legality of technical pesticide production facilities and issues an announcement approving production. This process is referred to as the “National Designated Pesticide Production Site.”
✔ (4) Finally, enterprise apply for pesticide production licenses from two different departments based on the production approval announcement issued by the MIIT.
– For General pesticides, enterprise must apply for a pesticide production license from the MIIT; which is the “Pesticide Production Approval Certificate.”
– For National standard pesticides, enterprise must apply for a pesticide production license from the General Administration of Quality Supervision, Inspection and Quarantine (AQSIQ), which is the “National Industrial Product Production License.”
With the promulgation of the new Pesticide Law in 2017, the two production license-issuing departments (AQSIQ and MIIT) were fully taken over by the MOA. This marks the completion of the industrial revolution in China’s Pesticide Industry after more than two decades of development and reform.
# Latest update: In 2024, the State Administration for Market Regulation (SAMR, former AQSIQ) and the Standardization Administration of China (SAC) released the first part of the GB 30000 series, titled “Classification of Chemical Labels Part 1: General Rules” (GB 30000.1-2024). This standard is technically consistent with the United Nations “Globally Harmonized System of Classification and Labelling of Chemicals” (GHS) (Eighth Edition) and will officially take effect on August 1, 2025.

China’s New Pesticide Law of 2017

(the new “Nationally designated restricted pesticide sales sites”)

(2017 – Present)

New China’s Pesticide Law
On Feb. 8, 2017, the State Council of China approved an amendment to the “Regulation on the Administration of Pesticides” – known as the State Decree No. 677, coinciding with repeal of the 2001 State Decree No. 326.
(https://www.gov.cn/gongbao/content/2017/content_5186961.htm)
“List of Restricted Pesticides (2017 Edition)”
On August 31, 2017, the Ministry of Agriculture (MOA) of China issued Announcement No. 2567, the “List of Restricted Pesticides,” which included a total of 32 pesticides. Among these, 22 pesticides are restricted to being sold only at sites designated by the state, including four coumarin-based rodenticides: “Warfarin (Restricted List#19), Coumatetralyl (Restricted List#20), Bromadiolone (Restricted List#21), and Brodifacoum (Restricted List#22).”
(http://www.moa.gov.cn/nybgb/2017/dsq/201802/t20180201_6136189.htm)
In 2018, the MOA was officially renamed the Ministry of Agriculture and Rural Affairs (MARA).
February 1, 2019: Siyang Rodenticide Factory passed the new “Nationally designated restricted pesticide sales sites” review by the MARA (previously by the MIIT and the AQSIQ) and obtained a new restricted pesticide license.
# Latest update: In September 2021, Siyang Rodenticide Factory completed its relocation and obtained a new MARA Restricted Pesticide License Number at its new location: (Su) 32000013199. This license is valid until September 14, 2026.
(http://nynct.jiangsu.gov.cn/art/2025/3/19/art_80243_11352.html)
Please click to view the MARA’s Restricted Pesticides License.

Mandatory Inspection of Bromadiolone and Brodifacoum exports

under the “2015 Directory of Hazardous Chemicals” and the “2017 Pesticides Law”

The General Administration of Customs (GAC) & the Ministry of Agriculture and Rural Affairs (MARA).

The export of pesticides from China is jointly regulated by the MOA and Customs. In China, the statutory tariff number for the pesticide “Brodifacoum” is “2932209011,” and the statutory tariff number for “Bromadiolone” is “2932209013.”

In 2018, AQSIQ merged with the newly established “State Administration for Market Regulation” (SAMR). At the same time, the AQSIQ’s “Entry-Exit Inspection and Quarantine” (well known CIQ, the “China Inspection and Quarantine”) management responsibilities and teams were transferred to the General Administration of Customs (GAC).
– http://www.customs.gov.cn/customs/ztzl86/302414/302415/zl70zn_fdxsd/2566516/2585161/index.html
December 18, 2020: The General Administration of Customs of China issued GAC Announcement No. 129 of 2020, the “Announcement on Issues Concerning the Inspection and Supervision of the Import and Export of Hazardous Chemicals and Their Packaging” in accordance with the “Regulations on the Management of Hazardous Chemicals (2011)” promulgated by the State Council Order No. 591 and the latest edition of the “Catalogue of Hazardous Chemicals (2015).” This announcement supersedes Announcement No. 30 issued by the former AQSIQ in 2012.
Mandatory inspections are required for the import and export of hazardous chemicals listed in the “Catalogue of Hazardous Chemicals (2015).” Relevant measures include: reporting the hazard category, UN hazard number, and UN packaging mark; providing the “Certification of Hazardous Classification and Identification,” “Performance Inspection Results of Packages for Transportation of Exported Goods,” and the “Certificate of Inspection for the Use of Packaging for the Transport of Dangerous Goods for Export”; and complying with UN TDG hazard classification and hazardous packaging requirements, as well as UN GHS labeling requirements.
There are 28 pesticides in the new “Catalogue of Hazardous Chemicals (2015)”, including three coumarin-based rodenticides as “Warfarin, Brodifacoum and Bromadiolone“.
(http://www.customs.gov.cn/customs/302249/302266/302267/3476363/index.html)
Dec 31, 2021, In order to implement the obligations of the “Rotterdam Convention”, the GAC and the MARA jointly issued “Announcement the No. 416” in accordance with the “Chinese Customs Law” and the “Regulation on Pesticide Administration”.
– http://www.customs.gov.cn/customs/ztzl86/302414/302415/zl70zn_fdxsd/2566516/2585161/index.html)
The latest version of the “Catalogue of the People’s Republic of China for the Administration of the Import and Export of Pesticides (2022 edition)” was published as an annex to the “Joint Announcement No. 416 of GAC and MARA.” This directory is commonly referred to as the “Chines Export Pesticide Customs Code.” The tariff code for pesticide export code #645 Brodifacoum, “2932209011,” and the tariff code for pesticide export code #640 Bromadiolone, “2932209013.” Both of these codes remain unchanged from the previous version.
(https://www.gov.cn/zhengce/zhengceku/2021-12/31/5665804/files/a690fececdf44b9aba505e6e40bb19ae.doc)

Siyang Rodenticide Factory

(1985 – 2025) – 40th Anniversary

Siyang Rodenticide Factory was established in March 1985, as the name implies, it is a professional rodenticide manufacturer located in Siyang County, China.

A leader in the development of rodenticides in China, the facotry has successfully challenged the industrial production of six anticoagulant rodenticides over the past few decades, including “Chlorophacinone, Warfarin, Coumatetralyl, Bromadiolone, Brodifacoum and Difenacoum.”

Two national rodenticides in China since 2006

Brodifacoum TC (GB 20690-2006), Statutory purity: 95% Min.

Bromadiolone TC (GB 20678-2006), Statutory purity: 97% Min.

In 2005, Siyang Rodenticide Factory participated in the Chinese Rodenticide Standards Review Meeting held by ICAMA (Institute for the Control of Agrochemicals, Ministry of Agriculture): all indicators for Bromadiolone and Brodifacoum were unanimously approved at the meeting, meaning that national standards will be further released.

In 2006, China SAC and AQSIQ (now SAMR) jointly enacted national standards (GB) for Brodifacoum and Bromadiolone, which came into effect in 2007.

The Revolution in Rodenticide Regulation in China (1985 -2025)

Currently, in 2025, the production and sale of technical rodenticides in China, such as Brodifacoum TC and Bromadiolone TC, will be mainly regulated by three national ministries: MPS, MEM and MARA.

In 1985, Siyang Rodenticide Factory was established with the approval of the former Ministry of Chemical Industry.

In 1997, China promulgated its first “Pesticide Management Regulations.”
Regulated by: ICAMA (the “Institute for the Control of Agrochemicals, MOA“).

In 1998, the State Council abolished the Ministry of Chemical Industry. (After the NDRC established in 2003 and introduced industrial policies in 2005, its final work was taken over by the MIIT established in 2008.)

In 2002, China promulgated its first “Law of the People’s Republic of China on Work Safety” (Work Safety Law),” the”Regulations on the Safety Management of Hazardous Chemicals,” and the“Catalogue of Hazardous Chemicals.” (Regulated by: SAWS, now MEM)

In 2005, China State Council promulgated the “2005 National Industrial Directive”, along with detailed “Industrial Policy Directory” issued by NDRC. (New rodenticide players and new rodenticide active ingredient are prohibited in China.)
In 2005, the Ministry of Public Security (MPS) promulgated the “Measures for the Administration of Permits for the Purchase and Road Transportation of Hypertoxic Chemicals.” (the effective regulations in force)
In 2007, the AQSIQ and the Standardization Administration of China (SAC) jointly promulgated the China national standards (GB) for Bromadiolone and Brodifacoum. (GB Production licensed by AQSIQ.)
In 2008, the MIIT was established, taking over some of the responsibilities of the NDRC. The ministry is primarily responsible for assessing and certifying technical-pesticide production sites by “national industrial policy” and issuing “qualified production site” announcements so that companies can further apply for pesticide production licenses from the MIIT (for general pesticides) or the AQSIQ (for GB pesticides.)
In 2012, the Ministry of Public Security (MPS) promulgated the GA 1002-2012 standard, namely the “Public Safety Protection Requirements for Storage Facilities of Hypertoxic Chemicals and Radioactive Sources.” (the effective regulations in force)
In 2015, a new “Catalogue of Hazardous Chemicals” was published, which included a “2015 list of Hypertoxic Chemicals.” (Regulated by: MPS and SAWS.)
In 2017, a new Pesticide Law was introduced, along with a new “2017 List of Restricted Pesticides.” The MOA took over the work of the MIIT and the AQSIQ. (MOA renamed the “Ministry of Agriculture and Rural Affairs” (MARA) in 2018)
In 2021, the China’s Work Safety Law which came into effect in 2002, underwent its third revision (the first revision was in 2009, and the second was in 2014). (Regulated by: the Ministry of Emergency Management, MEM, formerly SAWS)